Human Trisome Project: Latin America's DS Cohort Network
Official title: Human Trisome Project - Latin America Network
Funded at University of Colorado Denver · NIH-11594203 · Data updated 2026-11-12
A large, multi-site study of people with Down syndrome across the Americas to better understand health and aging in DS.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | September 20, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $269,244 |
| NIH project number | 3U01HD116469-02S1 |
| Project ID | NIH-11594203 on NIH RePORTER |
Who could benefit from this research
✓Could help
People with Down syndrome who may participate through one of the DS Cohort Research Sites in Colorado (USA) or across Latin America.
✕Less likely to help
Participants not directly engaged in the study or who do not meet the DS cohort criteria may not experience direct benefits.
What this research studies
This project connects six DS cohort sites, including five in Latin America, to share data and biospecimens as part of a broader Down Syndrome research program. Researchers are building on a common protocol and coordinating IRB approvals, trainings, and data-sharing to study how Down syndrome affects aging, health issues, and development. Participants would contribute information and samples as part of a coordinated, multi-site effort aimed at improving care and knowledge for people with Down syndrome. The work leverages existing clinical expertise and infrastructure to accelerate discoveries that could benefit DS individuals and their families.
Why it matters
Potential benefit: If successful, the study could reveal important factors influencing health and aging in Down syndrome and inform future interventions and care guidelines.
How similar studies have gone: This project builds on an established CDP/DS-4C framework with prior successful multi-site collaborations and common protocols.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Espinosa, Joaquin M. — University of Colorado Denver
- Study coordinator: Espinosa, Joaquin M.
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Human Trisome Project in Latin America Network
A large, multi-site study of people with Down syndrome across Latin America to better understand health and aging in DS.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.