Human Trisome Project — Latin America Network
Official title: Human Trisome Project - Latin America Network
Funded at University of Colorado Denver · NIH-11594204 · Data updated 2026-11-12
A multinational study of people with Down syndrome is expanding to Latin America to better understand health and aging in DS and share data across sites.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | September 20, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $269,406 |
| NIH project number | 3U01HD116469-02S2 |
| Project ID | NIH-11594204 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with Down syndrome ages across the lifespan who are enrolled or eligible for DS cohort research with participating sites in the CDP framework.
✕Less likely to help
People not connected to DS cohorts or not engaging with the participating sites may not directly benefit.
What this research studies
This project connects six Down syndrome cohort sites, including five in Latin America, to collect detailed health data and biospecimens. Researchers at the University of Colorado Denver and partner sites will follow a common protocol to harmonize measurements, regulatory processes, and data sharing with the CDP. The effort aims to uncover biological and clinical mechanisms driving outcomes in Down syndrome as people age, with a strong emphasis on collaboration and standardization across countries. Ongoing IRB approvals and phased recruitment support progress toward a large, diverse, multi-site DS cohort so future research can be more precise and inclusive.
Why it matters
Potential benefit: If successful, the study could improve understanding of Down syndrome progression and aging, informing better care and potential future interventions.
How similar studies have gone: Previous DS cohort collaborations under the CDP have shown promise in harmonizing data and enabling multi-site analyses.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Espinosa, Joaquin M. — University of Colorado Denver
- Study coordinator: Espinosa, Joaquin M.
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Human Trisome Project in Latin America Network
A large, multi-site study of people with Down syndrome across Latin America to better understand health and aging in DS.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.