NIH-funded research R01 grant

How the brain understands spoken language in autism

Official title: Functional organization of the superior temporal gyrus for speech perception

Funded at University of California, San Francisco · NIH-11361054 · Data updated 2026-11-12

Researchers study how the brain processes speech sounds so people with autism may benefit from improved communication therapies in the future.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startApril 1, 2012
Project endJuly 31, 2027
Funding year2026
Award (this year)$681,817
NIH project number5R01DC012379-15
Project IDNIH-11361054 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are individuals with autism or related speech-language challenges who are undergoing neurosurgical procedures permitting brain recordings.

Less likely to help

Patients not undergoing neurosurgical procedures or without language-processing difficulties may not directly benefit from these findings.

What this research studies

This project looks at how the brain transforms sounds into meaningful speech by recording brain activity from the surface during neurosurgical procedures. Using high-density electrode grids and advanced signal processing, researchers map how speech sounds are encoded in the superior temporal gyrus and related areas. The goal is to understand how consonants, vowels, and the rhythm of speech are represented and integrated to form understandable language. Findings could inform new approaches to speech therapy and communication strategies for individuals with autism who have language processing differences.

Why it matters

Potential benefit: A better understanding of how speech is represented in the brain could lead to improved language therapies and interventions for people with autism.

How similar studies have gone: Previous work has shown that brain recordings can reveal how speech sounds are represented, supporting the potential for meaningful advances, though this exact approach is relatively specialized.

Where this research is happening

  • University of California, San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Chang, Edward — University of California, San Francisco
  • Study coordinator: Chang, Edward

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.