How social isolation affects aging and health in people with schizophrenia

The impact of social isolation on aging health in schizophrenia

['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11371749

This project is tracking whether loneliness and lack of social contact are linked to earlier health problems in older adults living with schizophrenia.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11371749 on ClinicalTrials.gov

What this research studies

You would join a group of about 650 people (around 500 with schizophrenia and 150 comparison participants) enrolled from sites in Europe and the U.S. Researchers will collect information about your social contacts, health conditions, medications, and other health-related measures and follow you over time. They will combine these records into a single longitudinal database to look for patterns connecting social isolation with earlier onset of age-related medical problems. The team aims to use these patterns to pinpoint ways to help people with schizophrenia stay healthier as they age.

Who could benefit from this research

Good fit: Adults diagnosed with schizophrenia, especially those who are older or approaching age 65, are the primary candidates for this work.

Not a fit: People without schizophrenia or much younger adults are unlikely to directly benefit from the study's findings.

Why it matters

Potential benefit: If successful, the work could identify loneliness as a modifiable risk factor and lead to strategies to reduce premature health problems in people with schizophrenia.

How similar studies have performed: Smaller pilot studies have suggested links between social isolation and worse long-term health in schizophrenia, but this larger longitudinal effort is relatively novel.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.