NIH-funded research R01 grant

How social isolation affects aging and health in people with schizophrenia

Official title: The impact of social isolation on aging health in schizophrenia

Funded at Icahn School of Medicine at Mount Sinai · NIH-11371749 · Data updated 2026-11-12

This project is tracking whether loneliness and lack of social contact are linked to earlier health problems in older adults living with schizophrenia.

More Aging research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai
NIH-funded
Lab location1 site (New York, United States)
Project startAugust 15, 2022
Project endMay 31, 2027
Funding year2025
Award (this year)$102,812
NIH project number3R01MH128971-04S4
Project IDNIH-11371749 on NIH RePORTER

Who could benefit from this research

Could help

Adults diagnosed with schizophrenia, especially those who are older or approaching age 65, are the primary candidates for this work.

Less likely to help

People without schizophrenia or much younger adults are unlikely to directly benefit from the study's findings.

What this research studies

You would join a group of about 650 people (around 500 with schizophrenia and 150 comparison participants) enrolled from sites in Europe and the U.S. Researchers will collect information about your social contacts, health conditions, medications, and other health-related measures and follow you over time. They will combine these records into a single longitudinal database to look for patterns connecting social isolation with earlier onset of age-related medical problems. The team aims to use these patterns to pinpoint ways to help people with schizophrenia stay healthier as they age.

Why it matters

Potential benefit: If successful, the work could identify loneliness as a modifiable risk factor and lead to strategies to reduce premature health problems in people with schizophrenia.

How similar studies have gone: Smaller pilot studies have suggested links between social isolation and worse long-term health in schizophrenia, but this larger longitudinal effort is relatively novel.

Where this research is happening

  • Icahn School of Medicine at Mount Sinai
    New York, United States
    Active

Researchers

  • Principal investigator: Reichenberg, Abraham — Icahn School of Medicine at Mount Sinai
  • Study coordinator: Reichenberg, Abraham

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.