NIH-funded research R01 grant

How social isolation affects aging health in schizophrenia

Official title: The impact of social isolation on aging health in schizophrenia

Funded at Icahn School of Medicine at Mount Sinai · NIH-11383120 · Data updated 2026-11-12

This research looks at how being isolated socially might influence health and aging in people with schizophrenia.

More Aging research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai
NIH-funded
Lab location1 site (New York, United States)
Project startAugust 15, 2022
Project endMay 31, 2027
Funding year2026
Award (this year)$430,739
NIH project number5R01MH128971-05
Project IDNIH-11383120 on NIH RePORTER

Who could benefit from this research

Could help

Adults with schizophrenia or related disorders who have long-term follow-up data and can participate in a multinational study.

Less likely to help

Patients without access to or interest in long-term observational follow-up may not benefit.

What this research studies

People living with schizophrenia often face early aging and higher rates of health problems. This study will combine data from US and European sites to see whether social isolation accelerates aging and worsens medical conditions in this group. Researchers will analyze long-term health data, lifestyle factors, and biological markers to understand connections between isolation, aging, and health outcomes. The goal is to identify mechanisms and potential points for intervention that could improve longevity and quality of life for individuals with schizophrenia.

Why it matters

Potential benefit: If successful, findings could guide interventions to reduce isolation and improve aging-related health in people with schizophrenia.

How similar studies have gone: Previous work suggests social factors influence health, but this multinational approach with deep phenotyping is relatively novel.

Where this research is happening

  • Icahn School of Medicine at Mount Sinai
    New York, United States
    Active

Researchers

  • Principal investigator: Reichenberg, Abraham — Icahn School of Medicine at Mount Sinai
  • Study coordinator: Reichenberg, Abraham

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.