How mild traumatic brain injuries affect brain function and seizures in veterans with epilepsy
Interactions of traumatic brain injury with pre-existing mild epilepsy on thalamocortical dysfunction, sensory processing, and seizures
This study is looking at how mild traumatic brain injuries can affect brain function and lead to epilepsy in veterans, and it aims to find new ways to help improve their symptoms and overall quality of life.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10948906 on NIH RePORTER |
What this research studies
This research investigates the impact of mild traumatic brain injuries (mTBIs) on brain function and the development of epilepsy in veterans. It focuses on understanding how these injuries disrupt large-scale brain networks, which may lead to sensory processing issues and seizures. The study aims to explore new therapeutic approaches, such as brain stimulation, to alleviate symptoms and improve the quality of life for affected individuals. By examining the interactions between mTBI and pre-existing epilepsy, the research seeks to provide insights into effective treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans who have experienced mild traumatic brain injuries and have a history of epilepsy or sensory processing disorders.
Not a fit: Patients who have not experienced mild traumatic brain injuries or do not have epilepsy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly reduce seizures and improve sensory processing in veterans with mTBI and epilepsy.
How similar studies have performed: Previous studies have shown success in understanding brain network dysfunction in non-traumatic patients, suggesting potential for similar breakthroughs in this novel area of research.
Where this research is happening
Nashville, United States
- Veterans Health Administration — Nashville, United States (Active)
Researchers
- Principal investigator: Gallagher, Martin J — Veterans Health Administration
- Study coordinator: Gallagher, Martin J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.