NIH-funded research U01 cooperative agreement

How Medicaid expansion could help recently released people get medications for opioid use disorder and mental health care

Official title: CE25-149 - The effect of Medicaid expansion on medications for opioid use disorder, mental health care, and overdose mortality among formerly incarcerated people

Funded at Univ of North Carolina Chapel Hill · NIH-11422049 · Data updated 2026-11-12

This grant studies how extending Medicaid after release from jail or prison could help people with opioid use disorder and mental health needs stay on treatment and avoid overdose.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startSeptember 30, 2025
Project endSeptember 29, 2028
Funding year2026
Award (this year)$349,841
NIH project number5U01CE003821-02
Project IDNIH-11422049 on NIH RePORTER

Who could benefit from this research

Could help

Formerly incarcerated adults who are navigating Medicaid enrollment and access to MOUD and mental health services after release.

Less likely to help

Individuals not facing incarceration-related healthcare transitions or lacking Medicaid-related barriers may not directly benefit.

What this research studies

People leaving jail or prison often face barriers to care, which can lead to overdoses. This project uses large, individual-level data to understand how Medicaid expansion helps with linking to medications for OUD and mental health services after release. The goal is to uncover the mechanisms behind any benefits and why racial disparities may exist, with a focus on real-world pathways from enrollment to care. The study builds on prior findings showing improved MOUD access after pre-release enrollment, aiming to inform policy and program decisions that support sustained treatment after release. Work is conducted at the University of North Carolina at Chapel Hill under the NIH U01 mechanism.

Why it matters

Potential benefit: If successful, findings could guide policy changes to expand insurance-driven access to medications for OUD and mental health care for individuals transitioning from incarceration, potentially reducing overdose deaths.

How similar studies have gone: Prior studies suggest pre-release Medicaid enrollment improves MOUD access and reduces overdoses, but this project seeks to clarify mechanisms and equity gaps.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Ranapurwala, Shabbar I — Univ of North Carolina Chapel Hill
  • Study coordinator: Ranapurwala, Shabbar I

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.