NIH-funded research R01 grant

How air pollution affects heart disease recurrence

Official title: Statistical methods to characterize causal mechanisms by which air pollution affects the recurrence of cardiovascular events

Funded at University of Rochester · NIH-10660281 · Data updated 2026-11-12

This study is looking at how breathing in tiny air pollution particles might affect people who have heart problems, helping us understand how to better prevent heart issues and improve health policies for everyone.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Rochester
NIH-funded
Lab location1 site (Rochester, United States)
Project startSeptember 23, 2023
Project endAugust 31, 2026
Funding year2023
Award (this year)$1,790,052
NIH project number1R01ES034021-01A1
Project IDNIH-10660281 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals with a history of cardiovascular disease who are exposed to varying levels of air pollution.

Less likely to help

Patients without any history of cardiovascular disease or those living in areas with minimal air pollution may not benefit from this research.

What this research studies

This research investigates the ways in which exposure to air pollution, specifically fine particles like PM2.5, influences the recurrence of cardiovascular events. It aims to fill critical gaps in understanding how air pollution contributes to the progression of cardiovascular disease and the overall burden of illness. By developing new statistical methods, the study will analyze existing data to identify causal pathways and mediators that link air pollution exposure to heart health outcomes. This research is essential for informing public health policies and improving disease prevention strategies.

Why it matters

Potential benefit: If successful, this research could lead to better prevention strategies and policies that reduce the impact of air pollution on heart disease recurrence.

How similar studies have gone: While there is existing research on air pollution and cardiovascular disease, this study's focus on causal pathways and recurrent events represents a novel approach.

Where this research is happening

  • University of Rochester
    Rochester, United States
    Active

Researchers

  • Principal investigator: Strawderman, Robert — University of Rochester
  • Study coordinator: Strawderman, Robert

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.