How air pollution affects heart disease recurrence

Statistical methods to characterize causal mechanisms by which air pollution affects the recurrence of cardiovascular events

NIH-funded research University of Rochester · NIH-10660281

This study is looking at how breathing in tiny air pollution particles might affect people who have heart problems, helping us understand how to better prevent heart issues and improve health policies for everyone.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-10660281 on NIH RePORTER

What this research studies

This research investigates the ways in which exposure to air pollution, specifically fine particles like PM2.5, influences the recurrence of cardiovascular events. It aims to fill critical gaps in understanding how air pollution contributes to the progression of cardiovascular disease and the overall burden of illness. By developing new statistical methods, the study will analyze existing data to identify causal pathways and mediators that link air pollution exposure to heart health outcomes. This research is essential for informing public health policies and improving disease prevention strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with a history of cardiovascular disease who are exposed to varying levels of air pollution.

Not a fit: Patients without any history of cardiovascular disease or those living in areas with minimal air pollution may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better prevention strategies and policies that reduce the impact of air pollution on heart disease recurrence.

How similar studies have performed: While there is existing research on air pollution and cardiovascular disease, this study's focus on causal pathways and recurrent events represents a novel approach.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cardiovascular Diseasescardiovascular disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.