HOPE in Kyrgyzstan prisons: a kim of real-world help for people at risk of HIV
Official title: Accelerating HIV prevention in high-risk prison environments
Funded at Yale University · NIH-11455252 · Data updated 2026-11-12
A prison-based program called HOPE aims to help HIV prevention by boosting access to treatment and reducing stigma among inmates at high risk of HIV in Kyrgyzstan.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | August 15, 2025 |
| Project end | May 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $86,313 |
| NIH project number | 3R01DA062557-02S2 |
| Project ID | NIH-11455252 on NIH RePORTER |
Who could benefit from this research
✓Could help
Inmates in Kyrgyzstan prisons who have a history of injection drug use and are at high risk for HIV.
✕Less likely to help
Prisoners without injection drug use history or those not engaged in HIV prevention activities may see limited direct benefit.
What this research studies
This project tests HOPE, a 6-week, in-prison intervention designed to improve HIV prevention by increasing uptake of opioid agonist therapy and needle/syringe programs, while addressing mental health and addiction literacy. It builds on a prior K01 effort and uses a type 1 hybrid design to measure how well HOPE works and what helps or hinders implementation in a real prison setting. Participants include inmates with high HIV risk due to injecting drug use, with outcomes focused on service uptake, mental health, resilience, and stigma reduction. The study uses a structured program with mini-lectures, group discussions, and skills practice to empower participants and connect them with available resources. Results will inform future scale-up in similar high-risk prison environments.
Why it matters
Potential benefit: If successful, HOPE could reduce HIV transmission risk and improve access to prevention and treatment services for prisoners who inject drugs.
How similar studies have gone: Previous efforts showed challenges in increasing OAT uptake, but HOPE is designed to address barriers and may show meaningful improvements.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Rozanova, Julia — Yale University
- Study coordinator: Rozanova, Julia
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.