NIH-funded research NIH-funded research

HIV Prevention and Treatment Clinical Trials Unit at UNC

Official title: University of North Carolina Global HIV Prevention and Treatment Clinical Trials Unit

Funded at Univ of North Carolina Chapel Hill · NIH-11458533 · Data updated 2026-11-12

A UNC-led program will run multiple HIV prevention and treatment trials across the US and other regions to improve care for people living with HIV and those at risk.

More HIV Prevention research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startDecember 1, 2025
Project endNovember 30, 2027
Funding year2026
Award (this year)$105,363
NIH project number3UM1AI069423-20S1
Project IDNIH-11458533 on NIH RePORTER

Who could benefit from this research

Could help

Adults and adolescents living with HIV or at risk for HIV infection, including individuals with acute infection, adherence challenges, or drug resistance, across multiple global sites.

Less likely to help

Participants not living with HIV and not at risk for HIV would be less likely to benefit directly.

What this research studies

This program coordinates clinical trial activities across four NIH networks to advance HIV prevention, treatment, and vaccine strategies. It involves several experienced investigators and multiple clinical research sites in the US, Malawi, and Vietnam, enrolling adults and children living with HIV or at risk for infection. The unit will work with participants including newly diagnosed individuals, those on stable therapy, and those facing adherence or drug-resistance challenges, while coordinating with sites that manage co-infections like TB and HBV. The effort aims to translate findings into improved standards of care and prevention in diverse settings.

Why it matters

Potential benefit: Could lead to better HIV prevention methods, more effective treatment options, and improved care for people living with HIV and those at risk.

How similar studies have gone: Previous large multicenter HIV trials have informed current prevention and treatment guidelines and show promise for similar approaches now.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Eron, Joseph J — Univ of North Carolina Chapel Hill
  • Study coordinator: Eron, Joseph J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.