HIV aging, thinking skills, and everyday function in South Africa
Official title: Project 3 - Impairment and multimorbidity among people aging with HIV and ART in South Africa
Funded at Harvard University D/b/a Harvard School of Public Health · NIH-11399331 · Data updated 2026-11-12
A long-term study will help understand how aging with HIV and ART affects thinking, memory, physical abilities, and overall health in South Africa.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard University D/b/a Harvard School of Public Health NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 15, 2013 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $129,379 |
| NIH project number | 5P01AG041710-12 |
| Project ID | NIH-11399331 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults living with HIV who are aging and receiving ART in South Africa or similar HIV-endemic settings.
✕Less likely to help
People without HIV or those not aging may not directly benefit from this study.
What this research studies
This project looks at how people living with HIV who are aging and on ART experience cognitive and physical changes, and how these changes relate to other health conditions. Researchers will use data from HAALSI to measure prevalence of cognitive impairment, dementia, and multimorbidity, and identify drivers in HIV-affected communities in South Africa. The study builds on existing partnerships to track health and social outcomes over time, with a focus on policy-relevant findings. Participation involves data collection from adults living with HIV in targeted communities, with attention to consent and confidentiality.
Why it matters
Potential benefit: If successful, it could inform policies and programs to support healthy aging in people living with HIV in Africa.
How similar studies have gone: Previous HAALSI projects have demonstrated the value of longitudinal data for understanding aging and health in HIV populations.
Where this research is happening
-
Harvard University D/b/a Harvard School of Public Health
Boston, United States Active
Researchers
- Principal investigator: Barnighausen, Till — Harvard University D/b/a Harvard School of Public Health
- Study coordinator: Barnighausen, Till
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.