Caloric restriction in older adults with obesity: aging markers, frailty, and healthspan

Who could benefit from this research

What this research studies

This project tests whether short-term caloric restriction can positively affect biological aging markers and frailty in older adults with obesity. Researchers will monitor physical function, metabolic health, and aging-related biomarkers to understand potential healthspan benefits. The study is designed to connect biological aging signals with real-world health outcomes in a group at risk for obesity-related decline.

Why it matters

Where this research is happening

• Wake Forest University Health Sciences
  Winston-Salem, United States Active

Researchers

• Principal investigator: Houston, Denise Kathryn — Wake Forest University Health Sciences
• Study coordinator: Houston, Denise Kathryn

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.