A model to understand health challenges for older adults living with HIV

The CHARMED model: a multimorbidity simulation model for people aging with HIV

NIH-funded research Massachusetts General Hospital · NIH-11057631

This study is looking at the health issues older adults with HIV face, especially the risk of dementia, and aims to create a helpful model to find ways to improve their quality of life with personalized care strategies.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11057631 on NIH RePORTER

What this research studies

This research investigates the health challenges faced by older adults living with HIV, particularly focusing on the increased risk of dementia and other health conditions. It aims to develop a simulation model that can help identify effective interventions to improve the quality of life for these individuals. By analyzing the interplay between HIV, dementia, and other comorbidities, the research seeks to provide evidence-based recommendations for healthcare providers. Patients may benefit from tailored strategies that address their unique health needs as they age.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 50 and older who are living with HIV and may be at risk for dementia or other related health conditions.

Not a fit: Patients who are younger than 50 or do not have HIV may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes and quality of life for older adults living with HIV.

How similar studies have performed: Other research has shown success in addressing multimorbidity in aging populations, indicating that this approach has potential for meaningful impact.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.