A model to understand health challenges for older adults living with HIV
Official title: The CHARMED model: a multimorbidity simulation model for people aging with HIV
Funded at Massachusetts General Hospital · NIH-11057631 · Data updated 2026-11-12
This study is looking at the health issues older adults with HIV face, especially the risk of dementia, and aims to create a helpful model to find ways to improve their quality of life with personalized care strategies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | April 1, 2021 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $589,717 |
| NIH project number | 5R01AG069575-05 |
| Project ID | NIH-11057631 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 50 and older who are living with HIV and may be at risk for dementia or other related health conditions.
✕Less likely to help
Patients who are younger than 50 or do not have HIV may not receive any benefit from this research.
What this research studies
This research investigates the health challenges faced by older adults living with HIV, particularly focusing on the increased risk of dementia and other health conditions. It aims to develop a simulation model that can help identify effective interventions to improve the quality of life for these individuals. By analyzing the interplay between HIV, dementia, and other comorbidities, the research seeks to provide evidence-based recommendations for healthcare providers. Patients may benefit from tailored strategies that address their unique health needs as they age.
Why it matters
Potential benefit: If successful, this research could lead to improved health outcomes and quality of life for older adults living with HIV.
How similar studies have gone: Other research has shown success in addressing multimorbidity in aging populations, indicating that this approach has potential for meaningful impact.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Hyle, Emily Parker — Massachusetts General Hospital
- Study coordinator: Hyle, Emily Parker
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.