History of high blood pressure during pregnancy and heart risk in menopause
Official title: History of hypertensive pregnancy and cardiovascular risk during the menopause transition: a lifecourse approach
Funded at University of Washington · NIH-11431384 · Data updated 2026-11-12
This research looks at whether women who had high blood pressure problems during pregnancy have higher heart disease risk during and after menopause.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | September 1, 2026 |
| Project end | May 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $684,271 |
| NIH project number | 1R01AG103074-01 |
| Project ID | NIH-11431384 on NIH RePORTER |
Who could benefit from this research
✓Could help
Women with a history of hypertensive disorders during pregnancy, approaching or undergoing menopause, who can provide health data and biospecimens.
✕Less likely to help
Women without a history of hypertensive disorders during pregnancy may not directly benefit from this specific HDP-focused analysis.
What this research studies
The study follows women across midlife to see how previous hypertensive pregnancy events relate to changes in body, blood fats, inflammation, and overall cardiovascular risk as they go through menopause. Researchers will measure physical traits and circulating markers to identify a heart-attack risk profile linked to HDP history. The goal is to understand how menopause timing and hormone changes influence this risk, with the aim of guiding future prevention efforts.
Why it matters
Potential benefit: If successful, results could help identify women at higher heart risk after pregnancy, enabling earlier monitoring and personalized prevention.
How similar studies have gone: Previous research shows HDP history is linked to higher cardiovascular risk, supporting the potential value of this lifecourse approach.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Shree, Swati — University of Washington
- Study coordinator: Shree, Swati
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.