HPV and pregnancy risk: a big study following 1,280 pregnancies
Official title: Human papillomavirus and risk to pregnancy: a cohort study
Funded at University of Texas Med Br Galveston · NIH-11619930 · Data updated 2026-11-12
A large pregnancy study at UTMB looks at whether human papillomavirus (HPV) during pregnancy is linked to problems like preterm birth.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Med Br Galveston NIH-funded |
| Lab location | 1 site (Galveston, United States) |
| Project start | September 4, 2025 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $341,379 |
| NIH project number | 3R01AI184534-02S1 |
| Project ID | NIH-11619930 on NIH RePORTER |
Who could benefit from this research
✓Could help
Pregnant individuals or those planning pregnancy who are receiving care at the participating UTMB clinics and consent to participate.
✕Less likely to help
Participants whose pregnancy outcomes are not affected by HPV or who do not have HPV in the sampled tissues may not see direct benefit.
What this research studies
If you’re pregnant or planning pregnancy, this study could help us understand whether HPV in the cervix, amniotic fluid, or placenta affects pregnancy outcomes. Researchers will enroll about 1,280 pregnancies from three clinics, collecting samples and pregnancy data over time to look for links between HPV and preterm birth or other adverse outcomes. The goal is to clarify mixed findings and provide clearer information for patients and clinicians about HPV’s role in pregnancy health. This study is observational and involves following participants through their pregnancies and analyzing biological samples.
Why it matters
Potential benefit: Improved understanding of HPV’s role in pregnancy could lead to better risk assessment and guidance for expectant mothers.
How similar studies have gone: Previous prospective cohorts have shown mixed results; this study aims to provide more definitive evidence in a US population.
Where this research is happening
-
University of Texas Med Br Galveston
Galveston, United States Active
Researchers
- Principal investigator: Berenson, Abbey B — University of Texas Med Br Galveston
- Study coordinator: Berenson, Abbey B
Related research
Other NIH-funded projects on the same topics.
-
How air pollution during pregnancy affects fetal growth over time
This study looks at how air pollution affects the growth of babies in the womb during pregnancy, using ultrasound images to track changes over time, and it aims to help expectant parents understand when their babies might be most at risk from pollution.
-
Postoperative Pain Guidelines for Pregnancy: Safer, Patient-Centered Opioid Use
We’re creating patient-friendly guidelines to help doctors manage pain after delivery and surgery in pregnant people, aiming to reduce opioid overuse and improve safety.
-
Understanding how where you live and personal factors during pregnancy affect a child’s risk for obesity and metabolic problems
This project looks at how neighborhood conditions and individual factors during pregnancy may influence a child’s risk of obesity and metabolic health as they grow.
-
Blocking cancer-causing cMYC tricks after pregnancy changes in the breast
Researchers are testing how pregnancy and aging reshape the breast before cancer risk, using patient-reinformed models to see if it changes how dangerous cMYC signals behave.
-
SSRI use during pregnancy: effects on placental blood flow and inflammation
This grant studies how antidepressants (SSRIs) used during pregnancy might affect the placenta and inflammation, and whether a 5-HT2 receptor blocker could mitigate any negative effects.
-
California Abundant Birth Project: does guaranteed income during pregnancy affect birth outcomes and child development?
A government-backed program gives pregnant people in California monthly income to reduce stress, with researchers studying how this helps birth outcomes and early child development.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.