NIH-funded research R01 grant

Cardiovascular risk planning and reduction for men with prostate cancer

Official title: Cardiovascular Risk Prediction and Reduction in Men with Prostate Cancer

Funded at University of Pennsylvania · NIH-11627340 · Data updated 2026-11-12

A program to better predict and reduce heart disease risk in men treated for prostate cancer, especially older patients.

More Prostate Cancer research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startSeptember 25, 2025
Project endAugust 31, 2029
Funding year2026
Award (this year)$21,340
NIH project number3R01HL182015-02S1
Project IDNIH-11627340 on NIH RePORTER

Who could benefit from this research

Could help

Men with non-metastatic prostate cancer, particularly older adults undergoing or after androgen deprivation therapy.

Less likely to help

Patients without prostate cancer or without a cardiovascular risk concern may not benefit.

What this research studies

This project focuses on understanding why men with prostate cancer have higher heart-disease risk and how existing tools miss important cancer-related factors. Researchers will develop improved ways to estimate cardiovascular risk that include treatments like androgen deprivation therapy and competing health risks. They will test and refine risk tools to guide personalized prevention and management for individual patients. The goal is to help men stay healthier overall during and after prostate cancer care.

Why it matters

Potential benefit: If successful, patients could receive more personalized heart-disease prevention during prostate cancer treatment, potentially lowering heart-attack risk and improving longevity.

How similar studies have gone: Previous risk tools perform poorly in cancer patients; this project aims to improve on that with cancer-specific considerations.

Where this research is happening

  • University of Pennsylvania
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Ky, Bonnie — University of Pennsylvania
  • Study coordinator: Ky, Bonnie

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.