Hippocampal neurogenesis and its link to memory in Alzheimer’s disease

Who could benefit from this research

What this research studies

Researchers at the University of Illinois at Chicago will study human brain tissue from individuals with and without Alzheimer’s disease to understand if new hippocampal neurons appear and how they correlate with memory. The project builds on prior findings that neurogenesis may persist into old age but differs in Alzheimer’s. By examining brain samples and related data, the team aims to clarify whether promoting neurogenesis could support cognitive function in AD/ADRD. The findings could inform future approaches to protect memory and potentially guide therapeutic strategies.

Why it matters

Where this research is happening

• University of Illinois at Chicago
  Chicago, United States Active

Researchers

• Principal investigator: Lazarov, Orly — University of Illinois at Chicago
• Study coordinator: Lazarov, Orly

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.