How air quality and neighborhood design affect thinking and social connection in rural older adults

Cognitive Function, Air Quality, and Built Environment among Rural Residents at Risk for Alzheimer's Disease and Related Dementias

['FUNDING_R01'] · FLORIDA ATLANTIC UNIVERSITY · NIH-11311345

This project uses wearables and daily surveys to look at whether air pollution, local neighborhood features, and social isolation affect thinking and memory in middle-aged and older rural adults.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorFLORIDA ATLANTIC UNIVERSITY (nih funded)
Locations1 site (BOCA RATON, UNITED STATES)
Trial IDNIH-11311345 on ClinicalTrials.gov

What this research studies

If you live in five communities around Lake Okeechobee and are middle-aged or older without dementia, researchers will follow you for up to five years with regular memory checks and questionnaires about your social life. They will link your results to community measures of air quality and the built environment to see how local conditions relate to thinking and memory over time. A smaller group of 120 participants will wear Apple Watches for two months and complete short daily surveys, especially during periods of agricultural burning, to collect detailed activity and exposure data. The goal is to spot patterns that might explain accelerated cognitive decline in rural residents and suggest ways to reduce risk.

Who could benefit from this research

Good fit: Community-dwelling, dementia-free adults aged 21 and older living in the five Lake Okeechobee-area communities who can complete cognitive tests, surveys, and (for a subgroup) wear an Apple Watch are ideal candidates.

Not a fit: People with diagnosed dementia, those younger than 21, or residents who do not live in the target rural communities are unlikely to be eligible or to benefit directly from participation.

Why it matters

Potential benefit: If successful, this work could reveal environmental and social factors that raise dementia risk in rural adults and guide community or personal actions to protect thinking and memory.

How similar studies have performed: Prior research links air pollution and social isolation to worse cognition, but combining wearables, daily surveys, and community-level measures in a rural population is relatively new.

Where this research is happening

BOCA RATON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.