Gluten-sensing tech to help manage celiac disease with telemedicine
Official title: Evaluation of Novel Technologies to Improve Clinical Management of Celiac Disease: The GLUTECH Trial
Funded at Columbia University Health Sciences · NIH-11370183 · Data updated 2026-11-12
A study tests new gluten-detection tools used with online care to help adults with celiac disease manage their condition.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 15, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $1,552,120 |
| NIH project number | 5U01DK136523-04 |
| Project ID | NIH-11370183 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults 21 years and older with celiac disease who can participate in telemedicine visits and use at-home gluten-detection tools.
✕Less likely to help
Patients who do not use or have access to telemedicine, or cannot perform home gluten testing, may not benefit from this approach.
What this research studies
If you have celiac disease, this trial looks at whether portable gluten sensors and urine gluten tests used alongside telemedicine can help you monitor gluten exposure and improve your quality of life. Participants will use these tools while communicating with a dietitian and clinician through remote visits to guide dietary choices. The study aims to see if this approach reduces symptoms and complications like anemia or bone health problems compared with standard care.
Why it matters
Potential benefit: If successful, it could make managing a gluten-free diet easier and more accurate through convenient at-home testing and remote care.
How similar studies have gone: Other studies have shown that self-monitoring tools can improve awareness of gluten exposure, with promising results in related management approaches.
Where this research is happening
-
Columbia University Health Sciences
New York, United States Active
Researchers
- Principal investigator: Lebwohl, Benjamin — Columbia University Health Sciences
- Study coordinator: Lebwohl, Benjamin
Related research
Other NIH-funded projects on the same topics.
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Understanding how immune cells interact in celiac disease to guide healing
A study from the University of Chicago will follow people with celiac disease to understand how immune cells in the gut contribute to damage or healing when gluten is present or restricted.
-
NanoDiscs: a new way to calm the immune system in celiac disease
A new, protein-like particle called NanoDiscs is being developed to deliver safe targets to the immune system in people with celiac disease, with the goal of reducing reactions to gluten.
-
Tissue damage and healing in Celiac Disease
A broad study at the University of Chicago is exploring why some people with celiac disease keep having symptoms and tissue damage even when they try to follow a gluten-free diet.
-
Gluten-detection devices and telemedicine to help adults with celiac disease
This project looks at whether using portable gluten sensors and urine gluten tests together with telemedicine can help adults with celiac disease stick to a gluten-free diet and feel better.
-
Role of Transglutaminase 2 in Celiac Disease
A study from Stanford aims to understand how a specific enzyme, TG2, contributes to celiac disease and to test a potential gut-focused treatment that could one day help people avoid dietary controls.
-
Gluten-specific immune responses in a humanized mouse model of celiac disease
A study in a special mouse that carries human immune system pieces to understand how gluten triggers celiac disease and to test potential therapies.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.