NIH-funded research U01 cooperative agreement

Glaucoma screening that uses AI to catch the disease early

Official title: DP24-081 The Glaucoma and Retinopathy Screening Study

Funded at Massachusetts Eye and Ear Infirmary · NIH-11358973 · Data updated 2026-11-12

A new screening program uses AI-driven eye tests to detect glaucoma early, especially in underserved communities.

More Glaucoma research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionMassachusetts Eye and Ear Infirmary
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 30, 2024
Project endSeptember 29, 2029
Funding year2026
Award (this year)$750,000
NIH project number5U01DP006822-03
Project IDNIH-11358973 on NIH RePORTER

Who could benefit from this research

Could help

Adults at risk for glaucoma, including members of underserved minority communities who may not have regular access to eye care.

Less likely to help

Individuals without access barriers or with no risk factors may see little direct benefit.

What this research studies

This project aims to screen people for glaucoma using autonomous AI analysis of eye images and easy-to-use virtual tests, improving early detection before vision loss occurs. By focusing on underserved populations, the study seeks to reduce health inequities and prevent irreversible disability. The approach builds on advances in AI for eye health and adapts them for glaucoma screening to be practical in real-world clinic and community settings.

Why it matters

Potential benefit: If successful, it could enable earlier glaucoma detection, reducing preventable vision loss and disparities.

How similar studies have gone: Similar AI-based screening methods have shown promise in other eye diseases and are being extended to glaucoma; this study tests a focused application.

Where this research is happening

  • Massachusetts Eye and Ear Infirmary
    Boston, United States
    Active

Researchers

  • Principal investigator: Friedman, David S — Massachusetts Eye and Ear Infirmary
  • Study coordinator: Friedman, David S

Related research

Other NIH-funded projects on the same topics.

  • IOP and CSF Pressure in Glaucoma Risk

    This grant studies how eye pressure and cerebrospinal fluid pressure together influence glaucoma risk and vision loss.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11644421

  • Comparing tube positions in glaucoma implants to protect corneal cells

    This trial compares two tube placements for glaucoma drainage implants to see which better protects corneal cells and controls eye pressure in people with uncontrolled glaucoma.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11520347

  • Automated topographic test for glaucoma detection and progression

    A new automated method uses topographic structure-function mapping to help diagnose glaucoma earlier and track its progression in patients.

    NIH research Columbia University Health Sciences · New York, United States · NIH-11516608

  • Using AI on eye scans and genes to predict glaucoma risk

    This project uses artificial intelligence on eye scans, vision tests, and genetic information to find people most likely to develop or have worsening glaucoma.

    NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11469603

  • AI-based glaucoma screening in community health centers

    A new, easy-to-use AI screening approach will be tested in federally funded health centers to help identify people at risk for glaucoma, especially in communities with higher risk.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11454104

  • Understanding how glaucoma genes control eye cell function

    A long-term research project will study how genetic factors affect eye cells in adults with glaucoma to uncover new ideas for protecting vision.

    NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11450761

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.