Genetic profiling of childhood glaucoma in India
Funded at Massachusetts Eye and Ear Infirmary · NIH-11419200 · Data updated 2026-11-12
A study will analyze the genetic makeup of children with glaucoma in India to better understand the causes and improve future diagnoses.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Eye and Ear Infirmary NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 30, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $425,000 |
| NIH project number | 5R01EY036648-03 |
| Project ID | NIH-11419200 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children with childhood glaucoma in India and related affected individuals who have genetic data available or can contribute to genetic testing.
✕Less likely to help
Patients without childhood glaucoma or those not participating in genetic testing may not benefit directly.
What this research studies
This project will collect high-quality genetic data from 480 children with childhood glaucoma in India and compare it with data from known glaucoma genes. Researchers will look for both known and new gene mutations that contribute to the disease and will link genetic findings to clinical features. The effort involves international collaboration between Indian clinicians and U.S. investigators to translate genetic information into more accurate diagnoses. The goal is to fill gaps where many affected kids currently go without a molecular diagnosis and to pave the way for better, earlier treatment decisions.
Why it matters
Potential benefit: Better genetic understanding could lead to earlier diagnosis and more personalized care for children with glaucoma in India.
How similar studies have gone: Other studies have shown that broad genetic profiling can reveal both known and novel disease-causing genes in childhood glaucoma.
Where this research is happening
-
Massachusetts Eye and Ear Infirmary
Boston, United States Active
Researchers
- Principal investigator: Wiggs, Janey L — Massachusetts Eye and Ear Infirmary
- Study coordinator: Wiggs, Janey L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.