Genetic and Genomic Factors in Prostate Cancer among American Men
Official title: Genetic and Genomic Variation in Prostate Cancer
Funded at Dana-Farber Cancer Inst · NIH-11535326 · Data updated 2026-11-12
This grant studies how inherited genes and tumor genetics influence how often prostate cancer occurs and how it behaves in American men.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dana-Farber Cancer Inst NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | January 7, 2022 |
| Project end | April 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $48,417 |
| NIH project number | 3R01CA259200-05S3 |
| Project ID | NIH-11535326 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include men with prostate cancer or those at risk who have genetic or tumor data available for analysis.
✕Less likely to help
Patients without access to genetic or tumor data may see limited personal benefit from the study.
What this research studies
People with prostate cancer or those at risk may benefit as we learn which genetic and tumor features influence cancer development and progression. The project will look at common genetic variants and tumor changes to understand why prostate cancer occurs more often in certain groups and how it might respond to treatment. Researchers will analyze patient genetic data and tumor info to identify meaningful patterns that could guide future personalized care. The work aims to improve risk prediction and inform decisions about screening, prevention, and treatment. Findings could help tailor therapies to individuals based on their genetic and tumor profiles.
Why it matters
Potential benefit: Better understanding of genetic and tumor factors could lead to more accurate risk assessment and personalized treatment approaches for prostate cancer.
How similar studies have gone: Prior research has linked germline and somatic variations to prostate cancer incidence and progression, supporting a promising but ongoing area of discovery.
Where this research is happening
-
Dana-Farber Cancer Inst
Boston, United States Active
Researchers
- Principal investigator: Rebbeck, Timothy Richard — Dana-Farber Cancer Inst
- Study coordinator: Rebbeck, Timothy Richard
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.