Causal Protein Markers to Understand and Predict Prostate Cancer Risk in Africans and Europeans
Official title: Uncovering causal protein markers to improve prostate cancer etiology understanding and risk prediction in Africans and Europeans
Funded at Lsu Health Sciences Center · NIH-11611654 · Data updated 2026-11-12
A cancer research project looking at proteins linked to prostate cancer to better understand why it happens and how risk differs between African and European populations.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lsu Health Sciences Center NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project start | July 1, 2022 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $773,848 |
| NIH project number | 7R01CA263494-05 |
| Project ID | NIH-11611654 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are men at risk of prostate cancer or with a diagnosed condition, especially those from African or European backgrounds, who might contribute samples or data.
✕Less likely to help
Individuals without prostate cancer or those outside the studied populations may not directly benefit.
What this research studies
This project will study proteins involved in prostate cancer to understand why the disease develops and why risk varies across populations. It will use a novel study design to limit biases that often affect biomarker studies and compare findings between African and European groups. By identifying proteins causally related to cancer and improving risk prediction models, the work aims to enhance screening and early detection for diverse populations. The study is led by LSU Health Sciences Center in New Orleans and involves collaboration across researchers and clinicians.
Why it matters
Potential benefit: If successful, this work could lead to more accurate risk prediction and earlier detection of aggressive prostate cancer in diverse populations.
How similar studies have gone: Previous biomarker studies have shown inconsistent results; this project aims to overcome past limitations with a design focused on causality across populations.
Where this research is happening
-
Lsu Health Sciences Center
New Orleans, United States Active
Researchers
- Principal investigator: Wu, Lang — Lsu Health Sciences Center
- Study coordinator: Wu, Lang
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.