Effects of ADT on motivation and emotion in prostate cancer patients

Who could benefit from this research

What this research studies

If you are living with prostate cancer and considering or receiving ADT, this study follows patients over years to see how treatment may change motivation, emotion, and thinking, using brain imaging and other tests to track changes. Researchers will collect medical data, ask about mood and motivation, and look for patterns that could predict who is more affected. The goal is to better understand why some men experience cognitive or emotional changes with ADT and how to tailor care to alleviate these issues.

Why it matters

Where this research is happening

• VA Connecticut Healthcare System
  West Haven, United States Active

Researchers

• Principal investigator: Chao, Herta Huey-an — VA Connecticut Healthcare System
• Study coordinator: Chao, Herta Huey-an

Related research

Other NIH-funded projects on the same topics.

• How hormone therapy affects motivation and emotions in prostate cancer patients

  This study is looking at how hormone therapy for prostate cancer affects motivation and emotions in men, helping us understand the side effects they might face, like feeling more anxious or down, so we can better support their overall well-being during and after treatment.

  NIH research VA Connecticut Healthcare System · West Haven, United States · NIH-11043405

• Motivation for Alcohol Use in Humans and How It Can Be Measured

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  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11632189

• Cardiovascular risk planning and reduction for men with prostate cancer

  A program to better predict and reduce heart disease risk in men treated for prostate cancer, especially older patients.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11627340

• Causal Protein Markers to Understand and Predict Prostate Cancer Risk in Africans and Europeans

  A cancer research project looking at proteins linked to prostate cancer to better understand why it happens and how risk differs between African and European populations.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11611654

• Ethical multimodal AI platform to improve prostate cancer detection with ultrasound

  A patient-friendly AI system uses ultrasound and MRI information to help doctors better find prostate cancer, aiming to improve accuracy and access.

  NIH research Stanford University · Stanford, United States · NIH-11596787

• Characterizing epigenetic targets in prostate cancer to help AR-driven cancer

  A research project at MD Anderson aims to understand how epigenetic factors shape androgen receptor signaling in prostate cancer to find new ways to treat resistant forms of the disease.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11573812

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.