Exploring how brain receptor structures affect communication in different species
Official title: CRCNS: Linking receptorarchitecture and functional brain networks across species
Funded at Child Mind Institute, INC. · NIH-11083182 · Data updated 2026-11-12
This study is looking at how certain brain receptors affect communication in the brain across different animals, including humans, to help us better understand brain structure and function, which could lead to new insights into brain disorders.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Child Mind Institute, INC. NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 1, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $175,344 |
| NIH project number | 1R01MH139349-01 |
| Project ID | NIH-11083182 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with neurological conditions or those interested in the biological basis of brain function.
✕Less likely to help
Patients with conditions unrelated to brain receptor function or those not residing in the study's geographic area may not benefit from this research.
What this research studies
This research investigates the relationship between neurotransmitter receptors in the brain and how they influence neural communication across various species, including humans and different types of monkeys and rats. By using advanced imaging techniques and algorithms, the study aims to create detailed 3D maps of receptor distribution and analyze how these structures correlate with brain function. The project will utilize data from multiple species to improve our understanding of brain architecture and its evolution, potentially leading to better insights into brain disorders.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of brain disorders and lead to improved treatment strategies for conditions affecting neural communication.
How similar studies have gone: While the approach of linking receptor architecture to brain function is innovative, similar studies have shown promise in understanding brain disorders through cross-species comparisons.
Where this research is happening
-
Child Mind Institute, INC.
New York, United States Active
Researchers
- Principal investigator: Xu, Ting — Child Mind Institute, INC.
- Study coordinator: Xu, Ting
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.