NIH-funded research R01 grant

Developing tools to connect brain structure with its function in humans and monkeys

Official title: Tools for integrating brain microstructure with functional dynamics in human and non-human primates

Funded at Child Mind Institute, INC. · NIH-11110841 · Data updated 2026-11-12

This study is looking at how tiny details in the brain's structure affect how it works, which could help us learn more about brain diseases and how medications work, and it's designed for anyone interested in brain health, including patients and their families.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionChild Mind Institute, INC.
NIH-funded
Lab location1 site (New York, United States)
Project startMay 1, 2025
Project endFebruary 29, 2028
Funding year2025
Award (this year)$323,978
NIH project number1R01MH139565-01
Project IDNIH-11110841 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with neurological conditions or those interested in brain health and function.

Less likely to help

Patients with no neurological concerns or those not interested in brain research may not benefit from this research.

What this research studies

This research focuses on understanding how the structure of the brain at a microscopic level relates to its overall function. By creating advanced tools, researchers aim to link detailed brain maps with brain activity, which could help in understanding various brain diseases and the effects of medications. The project will enhance existing software to analyze brain imaging data from both humans and macaques, making it easier to study brain dynamics across species. This work is part of a larger initiative to advance brain research and improve our understanding of brain health.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment of brain disorders by linking brain structure to function.

How similar studies have gone: Other research initiatives have shown promise in linking brain structure to function, making this approach a continuation of successful methodologies.

Where this research is happening

  • Child Mind Institute, INC.
    New York, United States
    Active

Researchers

  • Principal investigator: Funck, Thomas — Child Mind Institute, INC.
  • Study coordinator: Funck, Thomas

Related research

Other NIH-funded projects on the same topics.

  • Connecting brain receptor maps with networks across species

    A multi-species study will map where neurotransmitter receptors sit in the brain and how that relates to brain networks, using humans and several animal models.

    NIH research Child Mind Institute, INC. · New York, United States · NIH-11379100

  • Connecting tiny brain structures to brain activity in humans and primates

    This project builds software tools that link small-scale brain structure to brain activity to help researchers understand brain function and disease.

    NIH research Child Mind Institute, INC. · New York, United States · NIH-11325436

  • Identifying brain-based autism subtypes

    Researchers are combining thousands of existing brain scans and clinical records from children and teens with and without autism to find consistent brain-connectivity patterns that might define different autism types.

    NIH research Child Mind Institute, INC. · New York, United States · NIH-11263648

  • How patterns of brain chemical receptors shape brain networks across species

    This project maps where chemical receptors sit in the brain and links those maps to brain activity in humans and several animal species to better understand how brains are organized.

    NIH research Child Mind Institute, INC. · New York, United States · NIH-11177058

  • Exploring how brain receptor structures affect communication in different species

    This study is looking at how certain brain receptors affect communication in the brain across different animals, including humans, to help us better understand brain structure and function, which could lead to new insights into brain disorders.

    NIH research Child Mind Institute, INC. · New York, United States · NIH-11083182

  • Identifying brain-based subtypes of autism spectrum disorder

    This study is looking to better understand autism by grouping people with similar brain connections, which could help create more personalized treatments for those with autism.

    NIH research Child Mind Institute, INC. · New York, United States · NIH-11015027

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.