NIH-funded research R01 grant

Identifying brain-based subtypes of autism spectrum disorder

Official title: A mega-analysis framework for delineating autism neurosubtypes

Funded at Child Mind Institute, INC. · NIH-11015027 · Data updated 2026-11-12

This study is looking to better understand autism by grouping people with similar brain connections, which could help create more personalized treatments for those with autism.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionChild Mind Institute, INC.
NIH-funded
Lab location1 site (New York, United States)
Project startApril 1, 2023
Project endJanuary 31, 2028
Funding year2025
Award (this year)$618,109
NIH project number5R01MH133334-03
Project IDNIH-11015027 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children and adolescents aged 6 to 18 years who have been diagnosed with autism spectrum disorder or are neurotypical.

Less likely to help

Patients outside the age range of 6 to 18 years or those without a diagnosis of autism spectrum disorder may not benefit from this research.

What this research studies

This research aims to improve understanding of autism spectrum disorder (ASD) by identifying specific brain-connectome-based subtypes. By analyzing large datasets of neuroimaging and clinical information, the researchers will categorize individuals with ASD into distinct groups based on their brain connectivity patterns. This approach seeks to address the variability in ASD symptoms and characteristics, potentially leading to more tailored and effective treatments. The study will utilize existing data from multiple large-scale autism research databases to ensure a robust analysis.

Why it matters

Potential benefit: If successful, this research could lead to more personalized treatment strategies for individuals with autism spectrum disorder.

How similar studies have gone: Previous research has shown promise in using neuroimaging data to identify subtypes of autism, indicating that this approach has potential for success.

Where this research is happening

  • Child Mind Institute, INC.
    New York, United States
    Active

Researchers

  • Principal investigator: Di Martino, Adriana — Child Mind Institute, INC.
  • Study coordinator: Di Martino, Adriana

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.