Connecting brain receptor maps with networks across species
Official title: CRCNS: Linking receptorarchitecture and functional brain networks across species
Funded at Child Mind Institute, INC. · NIH-11379100 · Data updated 2026-11-12
A multi-species study will map where neurotransmitter receptors sit in the brain and how that relates to brain networks, using humans and several animal models.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Child Mind Institute, INC. NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 1, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $169,069 |
| NIH project number | 5R01MH139349-03 |
| Project ID | NIH-11379100 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not applicable to patient volunteers in this grant.
✕Less likely to help
This research does not involve enrolling patients as participants.
What this research studies
This project will create high-resolution maps of receptor architecture in rats and marmosets and align them with human and macaque data to compare brain networks. Researchers will use a transfer-learning neural network and advanced graph-matching to fuse receptor maps with multimodal MRI data across four species. They will examine how receptor layouts relate to functional connectivity and lamination patterns to understand the evolution of brain organization. The results aim to enable better translation of animal findings to human brain function and disease.
Why it matters
Potential benefit: If successful, the work could improve our understanding of brain network organization and guide translational studies that rely on animal models to study human brain disorders.
How similar studies have gone: Previous work shows promise in cross-species brain mapping, with initial receptor and MRI data suggesting meaningful parallels across species.
Where this research is happening
-
Child Mind Institute, INC.
New York, United States Active
Researchers
- Principal investigator: Funck, Thomas — Child Mind Institute, INC.
- Study coordinator: Funck, Thomas
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.