Enhancing arm movement control after paralysis

Improving intracortical control of reaching after paralysis

NIH-funded research Cleveland Clinic Lerner Com-Cwru · NIH-10879119

This study is exploring a new way to help people with paralysis from spinal cord injuries move their arms again by using special technology that reads brain signals and stimulates muscles, so they can control their movements just by thinking about them.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCleveland Clinic Lerner Com-Cwru NIH-funded
Lab location1 site (Cleveland, United States)
Project IDNIH-10879119 on NIH RePORTER

What this research studies

This research focuses on improving the ability to control arm movements in individuals with paralysis caused by spinal cord injuries. It utilizes advanced technology, including implanted microelectrodes that detect brain signals and stimulating electrodes that activate muscles, to restore movement. The study aims to refine algorithms that translate brain activity into precise muscle stimulation, allowing patients to move their arms using their thoughts. By testing these methods in both human and animal models, the research seeks to develop effective strategies for regaining independence in daily activities.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with cervical spinal cord injuries resulting in paralysis of the arms.

Not a fit: Patients with complete paralysis that cannot be addressed by current technological interventions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly enhance the quality of life for individuals with paralysis by restoring their ability to perform daily tasks independently.

How similar studies have performed: Previous research has shown promise in using similar technologies to restore movement in patients with paralysis, indicating a potential for success in this approach.

Where this research is happening

Cleveland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.