Effects of hormonal contraception on brain function and behavior
Official title: Neurobiology of hormonal contraception
Funded at University of Colorado Denver · NIH-11011440 · Data updated 2026-11-12
This study is looking at how a common birth control pill affects women's motivation and sexual feelings, to help find ways to make contraception better and more comfortable for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | March 15, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $160,801 |
| NIH project number | 5K23HD110435-03 |
| Project ID | NIH-11011440 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are reproductive-aged women who are considering or currently using hormonal contraception.
✕Less likely to help
Patients who are not using hormonal contraception or those who have contraindications to its use may not benefit from this research.
What this research studies
This research investigates how hormonal contraception, specifically the oral contraceptive containing ethynyl estradiol and levonorgestrel, affects brain reward processing and related behaviors in women. By using a placebo-controlled design, the study aims to understand the impact of these hormones on motivation and sexual function, which are critical factors influencing the use and discontinuation of contraceptives. The findings could lead to personalized treatment options that minimize negative side effects associated with hormonal contraception, ultimately improving patient satisfaction and adherence.
Why it matters
Potential benefit: If successful, this research could lead to improved hormonal contraceptive options that reduce negative mood and decreased sexual desire, enhancing overall patient satisfaction.
How similar studies have gone: Previous research has shown that hormonal treatments can significantly impact brain function and behavior, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Novick, Andrew Michael — University of Colorado Denver
- Study coordinator: Novick, Andrew Michael
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.