NIH-funded research R01 grant

Motivation for Alcohol Use in Humans and How It Can Be Measured

Official title: Translational underpinnings of motivation for alcohol in humans

Funded at University of California Los Angeles · NIH-11632189 · Data updated 2026-11-12

This grant explores how people are motivated to drink alcohol and tests a safe, controlled way to study that motivation to inform better treatments for alcohol use disorder.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles
NIH-funded
Lab location1 site (Los Angeles, United States)
Project startSeptember 17, 2026
Project endJuly 31, 2027
Funding year2026
Award (this year)$229,327
NIH project number3R01AA029701-04S1
Project IDNIH-11632189 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants include adults with alcohol use patterns who can safely participate in controlled alcohol administration studies.

Less likely to help

Individuals unable to participate in controlled alcohol infusion studies or who are not seeking treatment for AUD may not benefit.

What this research studies

Researchers at UCLA are building on previous work to translate what we know about alcohol use disorder into practical tests that can be used in people. The project uses a controlled infusion system to measure how hard someone will work to receive more alcohol, helping us understand what drives craving and use. By studying motivation in humans, the work aims to bridge findings from animal and laboratory studies to real-world treatment approaches.

Why it matters

Potential benefit: If successful, the research could lead to better strategies for reducing the urge to drink and improving personalized interventions for AUD.

How similar studies have gone: Previous translational work has shown that laboratory tasks can reflect real-world drinking motivation, though results vary by individual.

Where this research is happening

  • University of California Los Angeles
    Los Angeles, United States
    Active

Researchers

  • Principal investigator: Ray, Lara a. — University of California Los Angeles
  • Study coordinator: Ray, Lara a.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.