EASE-ENDO: A Mind-Body Virtual Group to Help Endometriosis-Related Pain
Official title: Empowerment, Acceptance, and Skill Enhancement for Endometriosis (EASE-ENDO): A Mind-Body Virtual Group Intervention for Endometriosis-Associated Pain
Funded at Massachusetts General Hospital · NIH-11289289 · Data updated 2026-11-12
A group video program designed to empower people with endometriosis to manage pain and improve daily life through mind-body strategies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 20, 2026 |
| Project end | June 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $742,500 |
| NIH project number | 1R34AT013246-01A1 |
| Project ID | NIH-11289289 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with endometriosis experiencing chronic pelvic pain who are interested in mind-body approaches delivered virtually.
✕Less likely to help
Individuals seeking pharmacological-only treatments or those unable to participate in live video sessions may not benefit.
What this research studies
This project aims to create and test a live video, 8-session group intervention called EASE-ENDO to support people with endometriosis-associated pain. It focuses on empowerment, acceptance, and teaching practical skills to cope with chronic pain in everyday activities. The team will assess feasibility and acceptability to see if patients find the format helpful and easy to participate in from home.
Why it matters
Potential benefit: If successful, patients could experience reduced pain impact and better quality of life through accessible online support and skills training.
How similar studies have gone: Prior mind-body and group-based interventions have shown promise for chronic pain, but this specific endometriosis-focused virtual program is novel.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Grunberg, Victoria Ann — Massachusetts General Hospital
- Study coordinator: Grunberg, Victoria Ann
Related research
Other NIH-funded projects on the same topics.
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Molecular clues to endometriosis-related infertility
This grant explores how molecular changes in endometriosis contribute to infertility, with the aim of finding better ways to diagnose and treat the condition.
-
Hormonal Influences on Inflammation in Endometriosis
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-
How genes influence endometriosis in women of different racial and ethnic backgrounds
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-
Quantum diamond sensor endoscopy to map iron in endometriosis
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Understanding how RPLP1 affects endometriosis and adenomyosis
A patient-focused look at how a ribosomal protein called RPLP1 may drive tissue changes in endometriosis and adenomyosis and what this could mean for future therapies.
-
CXCR4 methylation in endometriosis and its role as an early biomarker and non-hormonal therapy target
This project explores how changes in CXCR4 gene regulation may help diagnose endometriosis earlier and point toward non-hormonal treatments for the condition.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.