NIH-funded research NIH-funded research

Developing predictive models for frailty in heart failure patients using electronic health records.

Official title: Using Large Electronic Health Records and Advanced Analytics to Develop Predictive Frailty Trajectories in Patients with Heart Failure

Funded at Baylor College of Medicine · NIH-10866399 · Data updated 2026-11-12

This study is looking at how frailty affects older adults with heart failure by using health records to find patterns and risks, with the goal of helping doctors make better decisions for patient care.

More Heart Failure research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBaylor College of Medicine
NIH-funded
Lab location1 site (Houston, United States)
Project startJuly 1, 2020
Project endJune 30, 2025
Funding year2024
Award (this year)$143,942
NIH project number5K25HL152006-05
Project IDNIH-10866399 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 21 and older who have been diagnosed with heart failure and may exhibit signs of frailty.

Less likely to help

Patients who are younger than 21 or do not have heart failure may not benefit from this research.

What this research studies

This research aims to create advanced predictive models that assess frailty trajectories in patients with heart failure by utilizing large electronic health records (EHR). The approach involves analyzing clinical data to identify patterns and risk factors associated with frailty, which is a significant concern for older adults with chronic illnesses. By employing advanced computational techniques and clinical informatics, the research seeks to enhance understanding of how frailty impacts health outcomes and patient care. The ultimate goal is to improve clinical decision-making and patient management through better risk stratification.

Why it matters

Potential benefit: If successful, this research could lead to improved identification and management of frailty in heart failure patients, potentially enhancing their quality of life and reducing hospitalizations.

How similar studies have gone: Previous research has shown promise in using electronic health records for predictive modeling in various health conditions, indicating that this approach could be effective for frailty as well.

Where this research is happening

  • Baylor College of Medicine
    Houston, United States
    Active

Researchers

  • Principal investigator: Razjouyan, Javad — Baylor College of Medicine
  • Study coordinator: Razjouyan, Javad

Related research

Other NIH-funded projects on the same topics.

  • Impact of physical rehabilitation on frailty in heart failure patients

    This study is looking at how physical rehabilitation can help older heart failure patients, especially those who may be feeling weak, by checking changes in their blood and seeing if it helps them feel better and do everyday activities more easily.

    NIH research Boston University Medical Campus · Boston, United States · NIH-10864183

  • Understanding how physical frailty affects symptom management in heart failure patients

    This study is looking at how being physically frail affects adults with heart failure in recognizing and managing their symptoms, like shortness of breath, to help improve their health and find better ways to support them.

    NIH research Oregon Health & Science University · Portland, United States · NIH-10740609

  • Investigating frailty and aging in childhood cancer survivors

    This study is looking at childhood cancer survivors to see how they might face health challenges similar to older adults as they grow up, and it aims to find ways to help them stay strong and healthy by exploring treatments that could improve their well-being.

    NIH research St. Jude Children's Research Hospital · Memphis, United States · NIH-9890475

  • AI-supported heart failure diagnosis and management in Rwanda

    Aiming to help people with suspected heart failure in Rwanda get faster, more accurate diagnoses and better care using AI-guided ultrasound and care protocols.

    NIH research Boston Medical Center · Boston, United States · NIH-11625877

  • AI-assisted heart failure diagnosis in Rwanda using focused ultrasound

    An NIH-funded project will test whether AI-enhanced, easy-to-use heart ultrasound can help non-experts diagnose and manage heart failure in Rwanda.

    NIH research Boston Medical Center · Boston, United States · NIH-11625876

  • HF endotypes in heart failure using ethical multi-modal AI and molecular data

    A patient-friendly project that uses advanced AI and multiple kinds of health data to identify distinct heart failure subtypes that could guide personalized care.

    NIH research University of Washington · Seattle, United States · NIH-11621806

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.