Impact of physical rehabilitation on frailty in heart failure patients
Effect of physical rehabilitation on molecular markers of frailty in heart failure
This study is looking at how physical rehabilitation can help older heart failure patients, especially those who may be feeling weak, by checking changes in their blood and seeing if it helps them feel better and do everyday activities more easily.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10864183 on NIH RePORTER |
What this research studies
This research investigates how physical rehabilitation can improve health outcomes for patients with heart failure, particularly those who are older and may also be experiencing frailty. The study will assess various biological markers to understand the relationship between rehabilitation and frailty in heart failure patients. By analyzing over 1000 proteins in the blood, researchers aim to identify specific changes that occur with rehabilitation, which could lead to better treatment strategies. Patients will be monitored for improvements in their ability to perform daily activities and overall quality of life.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults diagnosed with heart failure, particularly those exhibiting signs of frailty.
Not a fit: Patients who are younger than 21 or do not have heart failure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective rehabilitation strategies that significantly improve the quality of life for heart failure patients.
How similar studies have performed: Previous studies have shown promising results in improving outcomes for heart failure patients through rehabilitation, indicating that this approach has potential for success.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Nayor, Matthew G. — Boston University Medical Campus
- Study coordinator: Nayor, Matthew G.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.