Understanding how physical frailty affects symptom management in heart failure patients

Physical Frailty and Symptom Monitoring and Management Behaviors in Heart Failure (PRISM-HF)

['FUNDING_R21'] · OREGON HEALTH & SCIENCE UNIVERSITY · NIH-10740609

This study is looking at how being physically frail affects adults with heart failure in recognizing and managing their symptoms, like shortness of breath, to help improve their health and find better ways to support them.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorOREGON HEALTH & SCIENCE UNIVERSITY (nih funded)
Locations1 site (PORTLAND, UNITED STATES)
Trial IDNIH-10740609 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between physical frailty and symptom monitoring and management behaviors in adults with heart failure. It aims to understand how frailty impacts patients' ability to recognize and respond to symptoms like breathlessness, which is crucial for improving health outcomes. By examining both the biological and behavioral profiles of these patients, the study seeks to develop effective interventions that can help mitigate adverse outcomes associated with heart failure. The research will involve both quantitative and qualitative assessments to gather comprehensive data on patient experiences.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are diagnosed with heart failure and may also be experiencing physical frailty.

Not a fit: Patients who do not have heart failure or those who are not experiencing physical frailty may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for managing heart failure symptoms, ultimately enhancing patient quality of life.

How similar studies have performed: Previous research has shown promising results in understanding the impact of physical frailty on health outcomes in various conditions, suggesting that this approach could yield valuable insights.

Where this research is happening

PORTLAND, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.