Understanding how physical frailty affects symptom management in heart failure patients
Official title: Physical Frailty and Symptom Monitoring and Management Behaviors in Heart Failure (PRISM-HF)
Funded at Oregon Health & Science University · NIH-10740609 · Data updated 2026-11-12
This study is looking at how being physically frail affects adults with heart failure in recognizing and managing their symptoms, like shortness of breath, to help improve their health and find better ways to support them.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | September 19, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $417,702 |
| NIH project number | 1R21NR020059-01A1 |
| Project ID | NIH-10740609 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are diagnosed with heart failure and may also be experiencing physical frailty.
✕Less likely to help
Patients who do not have heart failure or those who are not experiencing physical frailty may not benefit from this research.
What this research studies
This research investigates the relationship between physical frailty and symptom monitoring and management behaviors in adults with heart failure. It aims to understand how frailty impacts patients' ability to recognize and respond to symptoms like breathlessness, which is crucial for improving health outcomes. By examining both the biological and behavioral profiles of these patients, the study seeks to develop effective interventions that can help mitigate adverse outcomes associated with heart failure. The research will involve both quantitative and qualitative assessments to gather comprehensive data on patient experiences.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing heart failure symptoms, ultimately enhancing patient quality of life.
How similar studies have gone: Previous research has shown promising results in understanding the impact of physical frailty on health outcomes in various conditions, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Oregon Health & Science University
Portland, United States Active
Researchers
- Principal investigator: Denfeld, Quin Eleanor — Oregon Health & Science University
- Study coordinator: Denfeld, Quin Eleanor
Related research
Other NIH-funded projects on the same topics.
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This study is looking at how frailty affects older adults with heart failure by using health records to find patterns and risks, with the goal of helping doctors make better decisions for patient care.
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Investigating frailty and aging in childhood cancer survivors
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AI-assisted heart failure diagnosis in Rwanda using focused ultrasound
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HF endotypes in heart failure using ethical multi-modal AI and molecular data
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.