NIH-funded research R21 grant

Developing a new AI framework for better cancer treatment imaging

Official title: A Fully Decentralized Federated Learning Framework for Automated Image Segmentation in Cancer Radiotherapy

Funded at Columbia University Health Sciences · NIH-10831775 · Data updated 2026-11-12

This study is working on a new way to use artificial intelligence to help doctors better identify organs in CT scans for patients with liver and head and neck cancers who are getting radiation therapy, all while keeping your personal information safe and secure.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences
NIH-funded
Lab location1 site (New York, United States)
Project startSeptember 15, 2023
Project endAugust 31, 2025
Funding year2021
Award (this year)$442,664
NIH project number7R21EB030209-02
Project IDNIH-10831775 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients diagnosed with liver or head and neck cancers who are undergoing radiation therapy.

Less likely to help

Patients with cancers not involving the liver or head and neck, or those not receiving radiation therapy, may not benefit from this research.

What this research studies

This research focuses on creating an innovative decentralized framework that utilizes artificial intelligence to improve the accuracy of image segmentation in cancer radiotherapy. By allowing different institutions to train AI models on their local data without sharing sensitive patient information, the approach aims to enhance the generalization capabilities of these models across diverse clinical environments. The framework will specifically target automated organ segmentation in CT images for patients with liver and head and neck cancers undergoing radiation therapy, addressing a critical challenge in accurately delineating organs at risk during treatment.

Why it matters

Potential benefit: If successful, this research could lead to more precise and effective radiation therapy for cancer patients, improving treatment outcomes.

How similar studies have gone: Other research has shown promise in using decentralized AI approaches for medical imaging, indicating potential success for this novel method.

Where this research is happening

  • Columbia University Health Sciences
    New York, United States
    Active

Researchers

  • Principal investigator: Yuan, Yading — Columbia University Health Sciences
  • Study coordinator: Yuan, Yading

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.