Developing a device to help restore walking in people with partial paralysis
Preparing for a clinical trial to implement a fully implanted neuroprosthesis to restore walking after partial paralysis
This study is looking to help Veterans with spinal cord injuries, strokes, or multiple sclerosis walk better and more safely in their everyday lives by testing a special device that stimulates their muscles, and it’s making sure the device is safe for those who need regular MRI scans.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Louis Stokes Cleveland VA Medical Center NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10996763 on NIH RePORTER |
What this research studies
This research aims to enhance the ability of Veterans with incomplete spinal cord injuries, strokes, or multiple sclerosis to walk more effectively and safely in their communities. It focuses on a fully implanted neuroprosthesis that stimulates peripheral nerves to support weak or paralyzed muscles based on real-time feedback from the user's movements. The project will prepare for clinical trials by verifying essential pre-clinical tests, including MRI compatibility and battery life assessments, to ensure the device can be safely used by patients who require regular MRI scans.
Who could benefit from this research
Good fit: Ideal candidates include Veterans with incomplete spinal cord injuries, strokes, or multiple sclerosis who experience difficulties with walking.
Not a fit: Patients with complete paralysis or those who do not have conditions affecting their walking ability may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve mobility and independence for patients with partial paralysis.
How similar studies have performed: Previous research has shown promise in using neuroprosthetic devices for hand function, indicating potential for success in similar applications for walking.
Where this research is happening
Cleveland, United States
- Louis Stokes Cleveland VA Medical Center — Cleveland, United States (Active)
Researchers
- Principal investigator: Pinault, Gilles — Louis Stokes Cleveland VA Medical Center
- Study coordinator: Pinault, Gilles
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.