Delivering patient-facing guidelines for adults with sickle cell disease using a mobile app and booklets
Official title: Delivering Patient-Facing Evidence-Based Guidelines through mHealth to Adults with Sickle Cell Disease (PF-Guide)
Funded at Ohio State University · NIH-11402704 · Data updated 2026-11-12
A multi-center study will provide adults with sickle cell disease with easy-to-use, evidence-based guidelines through a mobile app and printed booklets.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | August 22, 2025 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $715,238 |
| NIH project number | 5R01HL174590-02 |
| Project ID | NIH-11402704 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with sickle cell disease who are able to use a smartphone and read printed materials.
✕Less likely to help
Patients who cannot access or use mobile apps or booklets, or those not interested in guideline-based care, may see limited benefit.
What this research studies
If you have sickle cell disease as an adult, this study will test a mobile app plus booklet guides designed to help you follow evidence-based care. Researchers will track how well the app and booklets help you understand and use guidelines to reduce health problems and hospital visits. The project builds on prior work showing patients want accessible, actionable information and that a combined digital and print approach is promising. The trial looks at real-world effectiveness and how easily clinics can implement these guidelines in routine care. It is conducted at multiple centers with adults who have SCD.
Why it matters
Potential benefit: If successful, patients could have clearer, more accessible guidelines to manage sickle cell disease and potentially fewer urgent healthcare visits.
How similar studies have gone: Preliminary data from a feasibility trial suggest that a mobile app plus booklets can engage adults with SCD and reduce healthcare utilization.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Cronin, Robert M — Ohio State University
- Study coordinator: Cronin, Robert M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.