NIH-funded research R01 grant

Defining postpartum PTSD and its impact on new mothers and their babies

Official title: Defining postpartum PTSD and its implications for maternal wellness and child development

Funded at Massachusetts General Hospital · NIH-11359755 · Data updated 2026-11-12

A long-term study follows pregnant women and their babies to better understand postpartum PTSD and how it affects mothers and child development.

More PTSD research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startAugust 16, 2022
Project endJuly 31, 2027
Funding year2026
Award (this year)$635,951
NIH project number5R01HD108619-05
Project IDNIH-11359755 on NIH RePORTER

Who could benefit from this research

Could help

Pregnant women in their third trimester and their infants up to 12 months postpartum who consent to participate.

Less likely to help

Women without access to study participation or those who do not meet the inclusion criteria may not receive direct benefits.

What this research studies

This study will enroll women in their third trimester and follow them from hours after birth through the first year after delivery, with parallel assessments of their babies. It will collect data on mood, bonding, and potential risk factors for postpartum PTSD while tracking infant development at key milestones. Researchers will use longitudinal surveys, clinical interviews, and possibly biological samples to map how maternal PTSD symptoms emerge and influence early mother–child interactions. The goal is to build a foundation for earlier identification and intervention to protect both mothers and their children.

Why it matters

Potential benefit: If successful, findings could lead to earlier detection and better treatment for CB-PTSD, improving maternal well-being and child development.

How similar studies have gone: Previous work has linked postpartum mood disorders to child outcomes, but the CB-PTSD trajectory and its effects on bonding are less well defined, making this study notably exploratory with potential impactful insights.

Where this research is happening

  • Massachusetts General Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Dekel, Sharon — Massachusetts General Hospital
  • Study coordinator: Dekel, Sharon

Related research

Other NIH-funded projects on the same topics.

  • Postpartum PTSD: effects on mothers and early infant development

    This project follows pregnant people from late pregnancy through the first year after birth to learn how childbirth-related PTSD affects moms and their babies.

    NIH research Massachusetts General Hospital · Boston, United States · NIH-11228820

  • Understanding Postpartum PTSD and its Effects on Mothers and Babies

    This research aims to better understand childbirth-related posttraumatic stress disorder (CB-PTSD) and how it affects new mothers and their infants.

    NIH research Massachusetts General Hospital · Boston, United States · NIH-11136469

  • Understanding postpartum PTSD and its effects on mothers and children

    This study is looking at how postpartum posttraumatic stress disorder (CB-PTSD) affects new moms and their babies, by checking in with pregnant women in their last trimester and then following them and their little ones during the first year after birth to see how they’re doing and what might help.

    NIH research Massachusetts General Hospital · Boston, United States · NIH-11135764

  • Understanding postpartum PTSD and its effects on mothers and children

    This study is looking at how postpartum posttraumatic stress disorder affects new moms and their babies, by following pregnant women in their last trimester and checking in with them during their baby's first year to see how they're doing and bonding together, so we can find ways to help families who might be strugglin

    NIH research Massachusetts General Hospital · Boston, United States · NIH-10885980

  • Wearable tech to track blood loss during childbirth

    A wearable device monitors cardiovascular signals to detect postpartum hemorrhage early so clinicians can act quickly to protect mothers.

    NIH research Washington University · Saint Louis, United States · NIH-11627926

  • HIV treatment and postpartum weight help after birth in South Africa

    A small, patient-friendly study is testing a lay health worker–led program to support postpartum women living with HIV in staying on ART and managing weight.

    NIH research Hartford Hospital · Hartford, United States · NIH-11625634

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.