Postpartum PTSD: effects on mothers and early infant development

Defining postpartum PTSD and its implications for maternal wellness and child development

NIH-funded research Massachusetts General Hospital · NIH-11228820

This project follows pregnant people from late pregnancy through the first year after birth to learn how childbirth-related PTSD affects moms and their babies.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11228820 on NIH RePORTER

What this research studies

If you join, researchers will enroll you in the third trimester (around week 32), check in in the hours after delivery, and follow you at Day 1, Day 45, and months 3, 6, and 12 postpartum while your infant is seen at 6 and 12 months. You will complete symptom questionnaires and bonding and developmental checks across these visits to track mental health and parent–infant interaction over time. The study aims to find who is at risk for childbirth-related PTSD, how symptoms change across the first postpartum year, and whether maternal symptoms relate to early infant development. Findings are intended to point toward earlier detection and supports for mothers and babies.

Who could benefit from this research

Good fit: Pregnant people in their third trimester (around week 32) who can attend follow-up visits through the first postpartum year are the ideal candidates.

Not a fit: People who are not pregnant, are beyond the first postpartum year, or cannot attend follow-up visits are unlikely to benefit directly from participating.

Why it matters

Potential benefit: If successful, this work could lead to better recognition of postpartum PTSD and earlier supports to protect maternal wellness and infant development.

How similar studies have performed: Related research has documented postpartum depression, but longitudinal studies specifically focused on childbirth-related PTSD and its effects on infants are rare, so this approach is relatively novel.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.