Data infrastructure support for real-time opioid overdose prevention

Who could benefit from this research

What this research studies

This grant funds a high-quality informatics team to create and maintain data infrastructures that connect diverse opioid-related data sources. It focuses on making data Findable, Accessible, Interoperable, and Reusable (FAIR) so HD2A projects can work together efficiently. The work emphasizes real-time surveillance and cross-institution collaboration to improve prevention efforts. Clinicians, researchers, and public health partners could benefit from better data integration to inform decisions and policies. The project aims to remove technical barriers that slow data sharing and analysis across networks.

Why it matters

Where this research is happening

• Wake Forest University Health Sciences
  Winston-Salem, United States Active

Researchers

• Principal investigator: Adams, Meredith C. B. — Wake Forest University Health Sciences
• Study coordinator: Adams, Meredith C. B.

Related research

Other NIH-funded projects on the same topics.

• Targeting Reinforcement to Help Smokers with Opioid Use Disorder and Chronic Pain Quit

  A study to see if switching people who smoke and are on buprenorphine for opioid use disorder and chronic pain to cigarettes with very low nicotine can help them quit smoking.

  NIH research Duke University · Durham, United States · NIH-11384704

• Digital program to help Veterans with chronic pain and opioid-use disorder stay on treatment and feel better

  A web-based 9-week program helps Veterans on buprenorphine manage chronic pain and cravings from home.

  NIH research VA Connecticut Healthcare System · West Haven, United States · NIH-11340218

• Integrated care for people with chronic pain and opioid use disorder at Montefiore/Einstein

  This program compares non-drug options like yoga, physical therapy, counseling, and a smartphone support app for people living with chronic pain and opioid use disorder.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11311142

• Multi-omics look at risk and resilience to opioid use disorder in veterans with chronic pain

  This grant funds a mentored 5-year project to understand why some veterans with chronic pain are more likely to develop opioid use disorder and what factors help them stay resilient.

  NIH research Philadelphia VA Medical Center · Philadelphia, United States · NIH-11293772

• Very low nicotine cigarettes to help people on buprenorphine with chronic pain quit smoking

  This compares switching to very low nicotine cigarettes versus regular cigarettes for people with opioid use disorder who have chronic pain to see if it reduces smoking, cravings, withdrawal, and pain.

  NIH research Duke University · Durham, United States · NIH-11190972

• Whole-person care for chronic pain and opioid use disorder

  This program offers combined, personalized treatments to help people with long-term pain and opioid use disorder improve daily functioning and quality of life.

  NIH research University of New Mexico · Albuquerque, United States · NIH-11161508

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.