NIH-funded research R01 grant

Cultural variation in how spousal depressive symptoms relate to Alzheimer's and physical health

Official title: Cultural variation in the impact of spousal depressive symptoms on Alzheimer's Disease and physical health

Funded at Michigan State University · NIH-11332792 · Data updated 2026-11-12

A study looking at how a spouse’s depression levels might influence Alzheimer's progression and overall health across diverse cultural groups.

More s Disease research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMichigan State University
NIH-funded
Lab location1 site (East Lansing, United States)
Project startMay 15, 2025
Project endFebruary 28, 2030
Funding year2026
Award (this year)$355,404
NIH project number5R01AG089376-02
Project IDNIH-11332792 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are older adults and their spouses from diverse cultural backgrounds who have completed the harmonized panel studies.

Less likely to help

Individuals without older age or spousal relationships or those outside the studied datasets may not directly benefit.

What this research studies

This project uses existing longitudinal data from multiple studies to explore how depressive symptoms in spouses relate to aging, cognitive health, and dementia risk. By combining data from several large, harmonized datasets, researchers aim to identify patterns across different cultural contexts. The work is rooted in human aging and dementia and seeks to understand factors that could influence prevention and healthy aging for people at risk of Alzheimer's disease.

Why it matters

Potential benefit: If successful, findings could inform culturally tailored strategies to support mental health and cognitive well-being in older couples, potentially reducing dementia risk.

How similar studies have gone: Prior research links depressive symptoms to worse health and cognitive outcomes, but this project extends understanding across cultures using harmonized data.

Where this research is happening

  • Michigan State University
    East Lansing, United States
    Active

Researchers

  • Principal investigator: Chopik, William Joseph — Michigan State University
  • Study coordinator: Chopik, William Joseph

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.