How spousal depression affects Alzheimer's disease and health across cultures

Cultural variation in the impact of spousal depressive symptoms on Alzheimer's Disease and physical health

NIH-funded research Michigan State University · NIH-11129427

This study looks at how a spouse's feelings of depression can affect the health and thinking abilities of people with Alzheimer's disease, and it aims to help us understand these effects better across different cultures.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMichigan State University NIH-funded
Lab location1 site (East Lansing, United States)
Project IDNIH-11129427 on NIH RePORTER

What this research studies

This research investigates the impact of depressive symptoms in spouses on the health and cognitive decline of individuals with Alzheimer's disease (AD). By examining data from diverse cultural backgrounds, the study aims to identify how these depressive symptoms influence the risk of developing AD and related health issues. The approach includes analyzing individual and dyadic data from multiple panel studies to understand the broader implications of spousal mental health on aging populations. This research seeks to fill gaps in existing knowledge that primarily focuses on Western populations.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults experiencing cognitive decline or diagnosed with Alzheimer's disease, particularly those with spouses exhibiting depressive symptoms.

Not a fit: Patients without a spouse or those whose spouses do not exhibit depressive symptoms may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved interventions for individuals at risk of Alzheimer's disease by addressing the mental health of their spouses.

How similar studies have performed: While there is existing research on the impact of depressive symptoms on health, this study's focus on cultural variation in the context of Alzheimer's disease is relatively novel.

Where this research is happening

East Lansing, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndrome
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.