Creating personalized treatment plans for severe ulcerative colitis
Development of Patient-Tailored Adaptive Treatment Strategies for Acute Severe Ulcerative Colitis
This study is looking at new ways to personalize treatment for people with acute severe ulcerative colitis, so that each patient gets the best care based on how they respond to different medications, helping to improve their recovery and avoid emergency surgeries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11059232 on NIH RePORTER |
What this research studies
This research focuses on developing adaptive treatment strategies tailored to individual patients suffering from acute severe ulcerative colitis (ASUC). The approach aims to address the limitations of current one-size-fits-all treatments by considering the unique responses and clinical changes of each patient. By utilizing a combination of therapies, including corticosteroids and rescue medications, the research seeks to improve treatment outcomes and reduce the need for emergency surgeries. Patients will be monitored closely to adjust their treatment plans based on their specific needs and responses.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 18 and older who are experiencing acute severe ulcerative colitis.
Not a fit: Patients with mild ulcerative colitis or those who do not meet the age requirement may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with acute severe ulcerative colitis.
How similar studies have performed: Previous research has shown promise in developing personalized treatment strategies for inflammatory bowel diseases, indicating potential success for this approach.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Berinstein, Jeffrey — University of Michigan at Ann Arbor
- Study coordinator: Berinstein, Jeffrey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.