NIH-funded research R01 grant

Communication Bridge helps people with primary progressive aphasia talk more clearly

Official title: Communication Bridge: Optimizing an evidence-based intervention for individuals with primary progressive aphasia

Funded at University of Chicago · NIH-11412609 · Data updated 2026-11-12

Aimed at people with primary progressive aphasia, this project tests a speech-language and psychosocial program delivered by telepractice to improve daily communication and quality of life.

More Aphasia research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Chicago
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 15, 2017
Project endAugust 31, 2028
Funding year2026
Award (this year)$2,211,372
NIH project number5R01AG055425-10
Project IDNIH-11412609 on NIH RePORTER

Who could benefit from this research

Could help

Adults diagnosed with primary progressive aphasia and their care partners who can participate in telepractice sessions.

Less likely to help

Patients who cannot participate in telepractice or do not have communication impairments comparable to PPA may see limited benefit.

What this research studies

Primary progressive aphasia progressively impairs language, affecting daily conversations and social life. The team developed the Communication Bridge program and tested it in global telepractice delivery, showing gains in functional communication that lasted for at least six months. The current grant advances rigorous clinical trials to confirm benefits and build evidence-based guidelines for care. If successful, the program could become a standard non-drug option to help patients and their families communicate more effectively. The study will involve people with PPA and will examine how the intervention translates into real-world communication at home and in the community.

Why it matters

Potential benefit: If successful, patients with PPA and their care partners could experience clearer communication and better quality of life through a scalable, evidence-based program.

How similar studies have gone: Earlier trials (CB1 and CB2) demonstrated feasibility and improved communication, with benefits persisting over time.

Where this research is happening

  • University of Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Rogalski, Emily J — University of Chicago
  • Study coordinator: Rogalski, Emily J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.