NIH-funded research R01 grant

Improving communication support for people with primary progressive aphasia

Official title: Communication Bridge: Optimizing an evidence-based intervention for individuals with primary progressive aphasia

Funded at University of Chicago · NIH-11398724 · Data updated 2026-11-12

This project improves and delivers an evidence-based speech and communication program to help people with primary progressive aphasia and their care partners, including through telehealth.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Chicago
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 15, 2017
Project endAugust 31, 2028
Funding year2025
Award (this year)$455,717
NIH project number3R01AG055425-09S1
Project IDNIH-11398724 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are people diagnosed with primary progressive aphasia (PPA) and their communication partners, typically in early to moderate stages and able to take part in speech-language sessions in person or via telehealth.

Less likely to help

People with very advanced, nonverbal PPA, severe medical or cognitive conditions that prevent participation, or without access to required telehealth technology may not receive benefit from this intervention.

What this research studies

You would receive a staged speech-language and psychosocial program called Communication Bridge, delivered in sessions that can be done in person or by telehealth. Some participants are randomly assigned to different versions so researchers can compare which approaches work best for everyday communication. The team measures functional communication, social participation, and quality of life, with follow-ups to see if gains last over time. Earlier phases showed telepractice is feasible and produced maintained improvements, and this work refines and prepares the program for wider use.

Why it matters

Potential benefit: If successful, the program could improve everyday communication, social participation, and quality of life for people with PPA and provide practical strategies for their care partners.

How similar studies have gone: Earlier Communication Bridge trials (CB1 and CB2) demonstrated feasibility of telepractice delivery and showed maintained gains in functional communication at six months, so this work builds on promising results.

Where this research is happening

  • University of Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Rogalski, Emily J — University of Chicago
  • Study coordinator: Rogalski, Emily J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.