NIH-funded research R01 grant

Caregiver talk and infant brain development in babies at risk for autism

Official title: Caregiver Speech and Brain-Behavior Development in Infants At-Risk for ASD

Funded at University of Minnesota · NIH-11325007 · Data updated 2026-11-12

This project follows babies who have an older sibling with autism to see how everyday caregiver speech and babies’ brain and behavior grow together in the first year of life.

More Speech research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Minnesota
NIH-funded
Lab location1 site (Minneapolis, United States)
Project startMay 20, 2022
Project endApril 30, 2027
Funding year2026
Award (this year)$651,583
NIH project number5R01DC019660-05
Project IDNIH-11325007 on NIH RePORTER

Who could benefit from this research

Could help

Infants who have an older sibling with autism and are around 6 to 12 months old.

Less likely to help

Families not at high familial risk for autism or those outside the age window may not directly benefit.

What this research studies

If your child has an older sibling with autism, this study will observe how caregivers speak to their babies and how the babies’ brain and behavior develop over the first year. Researchers will collect home recordings of daily caregiver and infant speech when the babies are 6 and 12 months old, and also study play sessions in the lab using advanced analysis tools. The goal is to understand whether supportive caregiver talk might help reduce the risk or impact of autism symptoms before they appear. The study collaborates with the IBIS Network to build on a large existing cohort of high-risk infants. Participation could involve frequent but noninvasive assessments and family-friendly visits designed to minimize burden.

Why it matters

Potential benefit: Gaining knowledge about early factors that influence autism development could inform earlier, more effective interventions for at-risk infants.

How similar studies have gone: Related longitudinal work with high-risk infants has shown meaningful insights into early predictors and caregiver effects, making this approach promising.

Where this research is happening

  • University of Minnesota
    Minneapolis, United States
    Active

Researchers

  • Principal investigator: Swanson, Meghan Rae — University of Minnesota
  • Study coordinator: Swanson, Meghan Rae

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.