How caregiver speech affects brain and behavior development in infants at risk for autism.

Caregiver Speech and Brain-Behavior Development in Infants At-Risk for ASD

NIH-funded research University of Minnesota · NIH-11079667

This study is looking at how the way caregivers talk to their babies, especially those with an older sibling with autism, can help support their brain and behavior development in the first year of life, with the hope of finding ways to help them before any signs of autism appear.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Minnesota NIH-funded
Lab location1 site (Minneapolis, United States)
Project IDNIH-11079667 on NIH RePORTER

What this research studies

This research investigates how the speech of caregivers influences the brain and behavior development of infants who are at high risk for autism spectrum disorder (ASD). By focusing on infants with an older sibling diagnosed with autism, the study aims to understand the protective effects of caregiver interactions during the critical first year of life. Researchers will collect and analyze recordings of caregiver and infant speech during natural interactions at home, as well as during structured play sessions in a lab setting. The goal is to identify early indicators that could inform interventions for infants before the onset of ASD symptoms.

Who could benefit from this research

Good fit: Ideal candidates for this research are infants aged 0-12 months who have an older sibling diagnosed with autism spectrum disorder.

Not a fit: Infants without a familial history of autism or those who are not at high risk for developing autism may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to early interventions that enhance developmental outcomes for infants at risk for autism.

How similar studies have performed: Previous research has shown promising results in understanding early interventions for autism, making this approach both relevant and potentially impactful.

Where this research is happening

Minneapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.