Bone and soft tissue repair with a piezoelectric hydrogel for peri-implantitis care
Official title: Bone and soft tissue responses to a hydrogel with piezoelectric potential in conservative non-surgical peri-implantitis treatment
Funded at Oralbiolife INC · NIH-11312068 · Data updated 2026-11-12
A new gel-like material with piezoelectric properties is being tested to help repair bone and surrounding tissues around dental implants affected by peri-implantitis.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oralbiolife INC NIH-funded |
| Lab location | 1 site (Churchville, United States) |
| Project start | September 7, 2026 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $318,017 |
| NIH project number | 1R41DE035030-01A1 |
| Project ID | NIH-11312068 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with dental implants experiencing peri-implantitis who are candidates for non-surgical management and regenerative approaches.
✕Less likely to help
Patients with advanced disease requiring surgical intervention may not benefit from this approach.
What this research studies
This project explores how a specially designed hydrogel can influence bone and soft tissue healing around dental implants in patients with peri-implantitis. The study focuses on conservative, non-surgical management first, with attention to how the material interacts with bone and connective tissues to promote regeneration. Researchers will assess tissue responses and healing patterns over time to determine potential benefits for patients facing implant complications.
Why it matters
Potential benefit: If successful, this approach could improve bone and tissue healing around implants and reduce the need for more invasive treatments.
How similar studies have gone: Previous data suggest biomimetic and nanostructured materials can support tissue regeneration in dental contexts, but this specific piezoelectric hydrogel is novel.
Where this research is happening
-
Oralbiolife INC
Churchville, United States Active
Researchers
- Principal investigator: Santana, Ronaldo — Oralbiolife INC
- Study coordinator: Santana, Ronaldo
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.