Multi-functional 3D-Printed Dental Implants to Prevent Peri-Implant Infections
Official title: Multi-functional 3D Printed Dental Implants for Preventing Peri-implantitis
Funded at Cleveland State University · NIH-11337632 · Data updated 2026-11-12
A patient-friendly implant made with a special 3D-printed material that fights infection and helps bone integrate with the implant.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland State University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | August 12, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $646,751 |
| NIH project number | 5R01DE033364-03 |
| Project ID | NIH-11337632 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adults needing dental implants who are at risk for implant infections or require high-precision, patient-specific implants.
✕Less likely to help
Patients requiring implants that do not require antibacterial properties or those not suitable for 3D-printed materials may not benefit.
What this research studies
This project aims to create custom, 3D-printed dental implants that are both antibacterial and good at bonding with bone. The team will develop silver-doped bioceramic particles embedded in a PEEK polymer to form Ultra-PEEK implants. These implants are printable with common 3D printers and designed to reduce peri-implant infections while supporting strong osseointegration. The researchers will study how the composition and printing parameters affect strength, antibacterial behavior, and bone integration. The goal is a safer, more durable option for patients needing dental implants.
Why it matters
Potential benefit: If successful, patients could receive dental implants that lower infection risk and heal more reliably with their jawbone.
How similar studies have gone: Previous studies show promise for antibacterial, osseointegrating implants, but this approach combines a novel AgAMP-PEEK system with 3D printing for personalized implants.
Where this research is happening
-
Cleveland State University
Cleveland, United States Active
Researchers
- Principal investigator: Sikder, Prabaha — Cleveland State University
- Study coordinator: Sikder, Prabaha
Related research
Other NIH-funded projects on the same topics.
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Creating advanced dental implants to prevent infections
This study is testing a new kind of dental implant made just for you that helps prevent infections, using special materials and 3D printing to make it stronger and safer than regular implants.
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Robotic dental implants to deliver stem cells
A new wireless robotic implant approach aims to improve bone healing and implant stability by delivering stem cells directly at the implant site for people needing dental implants.
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Understanding how tiny blood vessels behave around dental implants
A study at Georgetown University looks at why blood vessels near dental implants leak and become inflamed, with the goal of spotting problems early in patients who have implants.
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Understanding and reversing blood vessel problems in peri-implant inflammation
A study will explore why blood vessels in mouth implants get inflamed and test a drug approach to reverse this process to protect implants.
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Bone and soft tissue repair with a piezoelectric hydrogel for peri-implantitis care
A new gel-like material with piezoelectric properties is being tested to help repair bone and surrounding tissues around dental implants affected by peri-implantitis.
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Using CCL2 to treat bone loss around dental implants
This study is looking at a new way to help people with peri-implantitis, a condition that causes inflammation and bone loss around dental implants, by using a special protein to help the body heal and keep the area healthy without needing surgery.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.